Answer:
Taxol induces the assembly of microtubules, while Nocodazole suppresses tubulin assembly
Explanation:
Taxol and nocodazole are antimitotic drugs, i.e., drugs that inhibit the progression through the cell cycle, which is useful for killing cancer cells. Microtubules are proteins that act as the 'skeleton of the cell', which need to be reorganized when cells replicate. These structures (microtubules) are composed of α and β-tubulin heterodimers which assemble into protofilaments of microtubules. Taxol is an antimitotic drug that induces the formation of microtubules, thereby inhibiting microtubules' reorganization during mitosis. In consequence, cells treated with Taxol enter into apoptosis (i.e., programmed cell death). Moreover, Nocodazole is known to induce microtubule disassembly by interfering with the polymerization of tubulin monomers. In consequence, Nocodazole is useful to depolymerize the microtubule cytoskeleton.
An animal that eats only plants is called a herbivore because it comes from herbs
Hypercalcemia is a condition in which the calcium<span> level in your blood is above normal. </span>Too much calcium<span> in your blood can weaken your bones, create kidney stones, and interfere with the way your heart and brain works. Hypercalcemia most commonly results from overactive parathyroid glands.</span>
Answer:
The answer is given below.
Explanation:
A tiny difference in a distant enhancer make a blond through DNA Looping.
DNA Looping can bring the enhancer bound by an activator physically closer to the promoter even if the enhancer is located far away along the DNA molecule.
DNA Looping.
When a protein or a set of complex proteins binds to 2 different sites of DNA simultaneously while looping out the interfering DNA.
Important of DNA Looping
- It regulates metabolism of DNA
- it is involved in transcriptional initiation of prokaryotic operons.
Answer:
2 meters (3 Gb of base pairs)
Explanation:
The human genome is composed of 3 billion (3 Gb) base pairs, which are organized in 23 pairs of chromosomes. Within the nucleus, DNA is compacted by histone proteins to form nucleosomes and these structures are then organized in chromatin fibers that undergone higher-order compaction. The compaction of chromatin fibers is accomplished by proteins and Matrix attachment DNA regions (MARs) that bind specifically to the nuclear matrix. In an unwound state, each cell nucleus in the human body has approximately 2 meters of DNA (if the DNA molecule would be stretched end-to-end).