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strojnjashka [21]
3 years ago
7

Why are polygenic diseases less suited to gene therapy?

Biology
1 answer:
Nadya [2.5K]3 years ago
3 0

Answer:

<u>Polygenic therapies are more likely to show </u><u>unintended effects</u><u> in other regions of the genome likely resulting in harmful diseases.</u>

<u />

Explanation:

Gene therapy involves biotechnological techniques that add or remove gene sequences in the genome. These are typically used in eliminating harmful genes that cause genetic diseases or disorders and are generally thought to improve an individual's quality of life.

Polygenic traits are controlled by several genes. Similarly, polygenic diseases may be caused by variations in several gene sequences. These include hypertension, heart disease, and diabetes. Polygenic therapies are more likely to show unintended effects in other regions of the genome, leading to other deleterious disease-causing effects.

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Write the name of amoeba found in water causentine dysentry .​
posledela

Answer:

Hello my lady

Explanation:

Follow me anime lover

4 0
3 years ago
In the root of which of the following are the xylems and phloems arranged in a ring? (A) Gymnosperms.(B) Eudicots.(C) All plants
Vera_Pavlovna [14]

Answer: option B) Eudicots

Explanation:

Xylem and the phloem comprises the vascular tissue of plants.

In eudicots, vascular bundles are arranged in a ring within the stem.

7 0
2 years ago
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There is a population of alien dogs, species Dogus Cute-ee-us, that live on the planet Woof. Their genomes and biology are amazi
kupik [55]

Answer:

c. 1:4:6:4:1

Explanation:

The term quantitative heritability refers to the transmission of a phenotypic trait in which expression depends on the additive effect of a series of genes.  

Polygenic heritability occurs when a trait results from the interaction of more than one gene. And these genes can also have more than two alleles. The action of many genes and alleles can cause many different combinations that are the reason for genotypic graduation.  

Quantitative traits are those that can be measure, such as longitude, weight, eggs laid per female, among others. In the exposed example, the measurable trait is the dog´s friendliness. These characters do not group individuals by any precise and clear categories. Instead, they group individuals in many different categories that depend on how the genes were intercrossed and distributed during meiosis. The result depends on the magnitude in which each allele contributes to the final phenotype and genotype. When they interact, they create a gradation in phenotypes, according to the level of contribution.  

In the exposed example, each dominant allele contributes with a higher level of friendliness.    

  • aabb → 0 = Unfriendly/Loner (although not aggressive);
  • Aabb, aaBb → 1 = Somewhat friendly/shy;
  • AAbb, AaBb, aaBB → 2 = Friendly;
  • AABb, aABB → 3 = Very friendly;
  • AABB → 4 = Maximally friendly.

Cross: between two dihybrid friendly dogs

Parentals) AaBb    x    AaBb

Gametes) AB, Ab, aB, ab

                AB, Ab, aB, ab

Punnett square)   AB       Ab       aB       ab

                   AB   AABB   AABb  AaBB  AaBb

                    Ab   AABb    AAbb  AaBb  Aabb

                    aB   AaBB    AaBb   aaBB   aaBb

                    ab    AaBb    Aabb   aaBb   aabb

F1) 1/16 AABB ⇒ 4 = Maximally friendly

    4/16 AABb + AaBB ⇒ 3 = Very friendly

    6/16 AAbb + AaBb + aaBB ⇒ 2 = Friendly

    4/16 Aabb + aaBb ⇒ 1 = Somewhat friendly/shy

    1/16 aabb ⇒ 0 = Unfriendly/Loner

The Phenotypic ratio is 1:4:6:4:1

   

6 0
3 years ago
Where is skeletal muscle found?
Diano4ka-milaya [45]
Your skeletal muscle is found between the bones
3 0
3 years ago
- Describe what happens to a fertilised egg cell before implantation in the uterus.​
dangina [55]

Answer:

During fertilization, the sperm and egg unite in one of the fallopian tubes to form a zygote. Then the zygote travels down the fallopian tube, where it becomes a morula. Once it reaches the uterus, the morula becomes a blastocyst. The blastocyst then burrows into the uterine lining — a process called implantation.

Explanation:

3 0
3 years ago
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