Glomerular filtrate is formed by the difference in force of hydrostatic and osmotic pressure. This physical force involves:
Bowman's capsule hydrostatic pressure: This includes the pressure that develops in the Bowman's capsule against the fluid to be filtrated expelled out by the glomerulus.
Glomerular hydrostatic pressure: The glomerulus is the main site of production of filtrate. It is higher than the average blood capillary hydrostatic pressure. It allows the water and solute molecules to be filtrated out of the plasma membrane.
Colloid osmotic pressure: The osmotic pressure which is generated by the large molecules is the colloid osmotic pressure. It is created by the plasma proteins. This pressure draws water from the glomerulus.
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