Answer:
FDA approves Pfizer booster shots for people who are 'high risk' or over 65. The US Food and Drug Administration on Wednesday authorized a booster dose of the Pfizer and BioNTech Covd-19 vaccine for those ages 65 and older and some high-risk Americans, paving the way for a quick rollout of the shots.
Explanation:
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Cancer de pulmon o allergy’s
Answer:
The best answer would be cognitive health (<em>thinking</em>)
Cognitive thinking is of or relating to the mental processes of perception, memory, judgment, and reasoning, as contrasted with emotional and volitional processes.
For children, they learn through experience per say, meaning that it is important to teach them to control their behaviors for the sake of their reasoning of how they deal with certain situations. Aggressive behavior must be controlled which is why it is important for children to learn to control it. Therefore, the best option would be, "Learning to control aggressive behaviors is important for children's cognitive health."
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