The answer I believe is number 1
For evolution to occur:
There must be genetic variation in a population. This provides variation on which natural selection can act. Then natural selection can act by selecting those species which are better adapted to the environmental conditions. Over time those animals that are best suited to the environment only will survive and reproduce. Those organisms successful genes will be preserved and eventually the gene frequency in the population will change, changing the overall characteristics of a population. This is how evolution occurs.
A codon is a sequence of three nucleotides in DNA or RNA that codes for either a particular amino acid or tells the cellular machinery to start or stop using the code. It isn't located anywhere specific.
Regulatory proteins control the cell cycle.
If the regulatory proteins are malfunctioning or absent, the cells may reproduce abnormally fast, causing a tumor.
The cell’s DNA is replicated or copied before cell division because it is important for the cell to have 2 DNA molecules because the cell is going to divide into 2. Each new cell need a 1 DNA