Blood clots will do this. Cutting off blood flow while also increasing blood pressure. Also, if the viscosity (thickness of the blood) is thick which will slow down the flow and cause the body to use more effort to pump blood.
The fly species Drosophila santomea is found only on a single small island. Thus, this fly is considered to be "Endemic".
Answer: Eagles mate sexually.
Explanation: Typically the male eagle mounts and humps the female eagle.
I believe the answer would be "Top Predators"