Induced depression of single neurons in brain areas with opiate receptors
- Enkephalin, applied microiontophoretically, depressed spontaneous and glutamate-induced firing of one neuron in frontal cortex, caudate nucleus, and periaqueductal gray matter, where enkephalin and high concentrations of opiate receptors are met.
- More than one depressions were blocked by the specific narcotic antagonist naloxone. The results are durable with a neurotransmitter or neuromodulator role for this new brain pentapeptide.
- Opium derivatives have been in medical use for the last 2000 years, and may be longer than any other class of drugs
- . The brain regions which was involved in these actions have been identified in some instances by local microinjection of pmole quantities of opioids.
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Answer:
don't now
Explanation:
I havent learned this yet try a web browser
A model for a company's revenue from selling a software package is R(p)=-2.5p² + 400p, where p is the price in dollars of the software. What price will maximize revenue? Find the maximum revenue.
Answer: p = $80, R = $16,000
Step-by-step explanation:
The maximum is the y-value of the Vertex.
Step 1: Use the Axis-Of-Symmetry (AOS) formula to find x:
x=
R(p) = -2.5p² + 400
a= -2.5 b=400
= 
=80
∴ In order to maximize the value, the company will sell the software package for $80
Step 2: Find the maximum by plugging the p-value (above) into the given equation.
R(80) = -2.5(80)² + 400(80)
= -16,000 + 32,000
= 16,000
Answer:
B
Explanation:
if you were a female and had this done to you, you would then understand.
Striated muscles contain repeating sarcomeres of overlapping arrays of long, thin actin and thicker myosin filaments. Myosin filaments contains the myosin heads, which are enzymes that can bind to actin, split and make use of the energy from ATP. When muscle contraction starts, myosin heads bind to actin, change their configuration on actin, liberating the products of ATP hydrolysis and causing slide of the actin and myosin filaments. The action of the proteins troponin and tropomyosin on the actin filaments regulates vertebrae striated muscle contraction. The release of calcium ions from the sarcoplasmic reticulum is triggered by the nervous stimulation which causes depolarization of muscle membrane. Calcium ions bind to troponin and thus cause or allow the tropomyosin strands on the actin filament to move so that the part of the actin surface where myosin heads need to bind is uncovered. Contraction then occurs and only stops when the sarcoplasmic reticulum pumps calcium out of the muscle interior.
So basically, what triggers the uncovering of the myosin binding site on actin is the calcium ions binding to troponin and changing configuration.
