Their course of action in altering metabolism is very similar because both of them interact with intracellular receptors (primarily the cytosolic receptors present in cytoplasm of the cell) and translocate into the nucleus for performing their desired goal (likely to synthesize a mRNA which can then be turned into a protein to get a desired action going)
The corticospinal tract can be defined as the white matter motor pathway that starts with the cerebral cortex and terminates at the lower motor neuron of the spinal cord. This controls the movement of the trunk and limbs.
If the corticospinal tract is affected at any level above the medulla the voluntary control over the movements will be affected on the contra-lateral side of the body.