To solve this, you would need to identify the number of amino acids (20) you are dealing with and the number of positions (8) that are available in your polypeptide. so that would come out to 20 x 20 x 20 x 20 x 20 x 20 x 20 x 20 = 20^8
The answer is D. Telegraph, telephone, cordless phone , mobile
To have the largest sample size also gives you more data, thus increasing the likelihood of accuracy