Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
Hi
The answer is called a mutation
Set up the equation.
Since gravity and liquid densities are fixed (for the most part), the height of the liquid is the largest variable in the equation. The equation reads as Pfluid = ρgh, where ρ is the density of the liquid, g is the acceleration of gravity, and h is the height of the liquid (or depth of the fluid)
It tends to resist rising.
Humidity. I think you need to work on your grammar a little bit pal, if you ever need help with ELA homework, hmu.
