The main objective of phase 3 trials is to verify the therapeutic action of a new substance in a large number of patients, essentially to determine the risk/benefit ratio. Before phase 3, the substance is not regarded as a drug, but after a positive phase 3 trial it becomes a drug.
The most appropriate step to manage the patient's symptoms as mentioned in question is Quadriceps strengthening exercises.
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What is quadriceps?</h2>
The Quadriceps femoris is one of the largest and most powerful muscle of the human body. The quadriceps femoris is both a hip flexor and a knee extensor. It is made up of four individual muscles; the rectus femoris, and three vastus muscles. They are one of the strongest muscles in the body and make up the majority of the thigh.
Anterior knee discomfort in young women is frequently caused by patellofemoral pain syndrome. Usually, chronic usage or misalignment is at blame for such discomfort. A patellofemoral compression test can simulate the discomfort. Exercises for stretching and strengthening of quadriceps are part of the initial therapy, along with activity modification and non-steroidal anti-inflammatory medications.
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Answer:
Heart failure
Explanation:
A client with heart failure has decreased cardiac output caused by the heart's decreased pumping ability. A buildup of fluid occurs, causing dyspnea, dependent edema, hepatomegaly, crackles, and jugular vein distention. A client with pulmonary embolism experiences acute shortness of breath, pleuritic chest pain, hemoptysis, and fever. A client with cardiac tamponade experiences muffled heart sounds, hypotension, and elevated central venous pressure. A client with tension pneumothorax has a deviated trachea and absent breath sounds on the affected side as well as dyspnea and jugular vein distention.
Significant drug interactions that occur with antiviral drugs arise most often when they are administered via systemic routes such as intravenously and orally.
