Answer:
G1/S checkpoint
Explanation:
G1/S checkpoint is one of the points in the cell cycle, between growth phase 1 and DNA synthesis phase, where a cell that has been damaged is sensed by DNA repair enzymes and further degraded by apoptosis. In cancer cells, there is mutation in these DNA repair enzymes and thus nothing to correct the cells from dividing even when damaged and thus there is no arrest of division and cells continue dividing
Answer:
These kinds of mutations are referred to as Lethal mutations
Explanation:
This type of mutation deleteriously affects the vital genes that are responsible for the core functions of the body. The heart supplies blood to the body organs for nutrients and oxygen while kidneys filter out toxins and end products of metabolism. Mutations in genes for development of these organs will be deadly.
The absolute number of molecules of drug required to elicit a response