The United States government treatment towards the Native Americans during the Manifest Destiny was poor. The idea of Manifest Destiny was to let settlers spread across America. Design to remove or destroy the native population and their culture in America. Americans drove towards westward to get access to land across entire America. The removal of American Indians from their native homelands began under Manifest Destiny.
This is a little tricky but if i had to say, the answer would be A ^-^ The Civil War still hadn't been that long ago, so people of different races still didn't have the same rights as the whites (hence segregation)