Question

Normal cells responds to contact inhibition. When they come into contact with other cells, they stop moving and dividing. This keeps the cell contained within their own tissues. How did the mutated (cancer) cells show the evidence that they do not respond to contact inhibition?

Answer 1

Answer:

Cancer is basically a disease of uncontrolled cell division. Its development and progression are usually linked to a series of changes in the activity of cell cycle regulators. For example, inhibitors of the cell cycle keep cells from dividing when conditions aren’t right, so too little activity of these inhibitors can promote cancer. Similarly, positive regulators of cell division can lead to cancer if they are too active. In most cases, these changes in activity are due to mutations in the genes that encode cell cycle regulator proteins.

Explanation: