The answer is B
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Answer:
c. Pyridostigmine binds to the acetylcholinesterase active site and prevents sarin from binding to and modifying the enzyme active site.
Explanation:
Sarin is a toxic compound which inhibits acetylcholinesterase enzyme. This enzyme degrades the neurotransmitter acetylcholine after the required muscle cell stimulation. In absence of its activity, acetylcholine is not degraded and the muscle cells are stimulated uncontrollably. The muscles are not able to relax which ultimately proves fatal for the victim.
Pyridostigmine is also an acetylcholinesterase inhibitor like Sarin. However its period of inhibition is short compared to organophosphorus inhibitors like sarin. It competes with sarin and replaces it in the active site of acetylcholinesterase. The enzyme is still inhibited but for a shorter time as compared to inhibition by Sarin. Hence after sometime, it becomes functional again and resumes its normal activity. Acetycholine starts getting degraded relaxing the muscles.
Answer:
''Mining" probably conjures several images. One familiar scene is of the old West, where prospectors blast the sides of mountains, tunnel through the earth, or pan at a river's edge for gold. Another is of environmental impacts of acid mine drainage from older mines that did not benefit from modern technology and management practices. The common view of mining is of environmental degradation. Few individuals outside the industry are aware of modern mining practices and associated business, environmental, and public policy issues (highlighted in Appendix A) or of how mining companies are responding to today's environmental challenges.
Explanation: