Casting rope is the answer
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Kupffer cells, also known as stellate macrophages due to their particular structure while viewed under a microscope, were first identified by scientist Karl Wilhelm von Kupffer, after whom the cells were named, in 1876.
These cells, whose origin is in the yolk sack during fetal development, later on move to the liver where they will stay and further differentiate into their mature versions.
These cells are part of the liver cells, and are found particularly on the walls of the sinusoids, where they perform their two most important tasks. First, these cells are part of the immune system, as they are essentially macrophages. However, their role is pretty unique, as they are responsible not just for phagocytosis of invading bacteria, and other pathogens, and initiating immune responses, but also, this cell plays a role in decomposing red blood cells who are dying, and taking up the hemoglobin from them to further break that into reusable globin, and the heme group, from which iron is further extracted to be re-used and also to create bilirrubin, a part of bile.
Finally, these cells have been found to be connected to hepatic cirrhosis, as in their process of detoxifying ethanol, they produce toxins that force the liver cells to produce collagen, and thus to become fibrous.
He was known for the "Allotey Formalism" which arose from his work on soft X-ray spectroscopy. He was the 1973 recipient of the UK Prince Philip Golden Award for his work in this area.
Source - Wikipedia
Answer:
The main difference between osteoarthritis and rheumatoid arthritis is the cause behind the joint symptoms. Osteoarthritis is caused by mechanical wear and tear on joints. Rheumatoid arthritis is an autoimmune disease in which the body's own immune system attacks the body's joints.
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