The best answer in this case is C, "the researchers applied creativity to solve a problem in running an experiment".
Distributing the computing load across the global community by sharing processing power is a creative response to tackle the challenge in simulating protein folding for the experiment. This does not change or reduce the scientific merits of the experiment, so we can discount the first two answers (a & b). Answer d talks about well established scientific techniques, although the question wasn't really centered around the specific techniques, so it's not as relevant an answer as C.
The littoral zone<span> is the part of a sea, lake or river that is close to the shore. In coastal environments the littoral zone extends from the </span>high water mark<span>, which is rarely inundated, to shoreline areas that are permanently submerged. It always includes this </span>intertidal zone<span> and is often used to mean the same as the intertidal zone. However, the meaning of "littoral zone" can extend well beyond the intertidal zone and that is you answer</span>