Original formula Listerine is 26.9% alcohol, making it approximately 54 proof. According to the US, one "standard" drink contains roughly 14 grams of "pure" alcohol—so one standard drink of Listerine is 2.2 fl. oz. (so there are about 23 standard drinks in one 1.5 L bottle of Listerine).
What on earth, please repeat the question clearer
Long-term potentiation (LTP) is considered a cellular correlate of learning and memory. The presence of G protein-activated inwardly rectifying K(+) (GIRK) channels near excitatory synapses on dendritic spines suggests their possible involvement in synaptic plasticity. However, whether activity-dependent regulation of channels affects excitatory synaptic plasticity is unknown. In a companion article we have reported activity-dependent regulation of GIRK channel density in cultured hippocampal neurons that requires activity oF receptors (NMDAR) and protein phosphatase-1 (PP1) and takes place within 15 min. In this study, we performed whole-cell recordings of cultured hippocampal neurons and found that NMDAR activation increases basal GIRK current and GIRK channel activation mediated by adenosine A(1) receptors, but not GABA(B) receptors. Given the similar involvement of NMDARs, adenosine receptors, and PP1 in depotentiation of LTP caused by low-frequency stimulation that immediately follows LTP-inducing high-frequency stimulation, we wondered whether NMDAR-induced increase in GIRK channel surface density and current may contribute to the molecular mechanisms underlying this specific depotentiation. Remarkably, GIRK2 null mutation or GIRK channel blockade abolishes depotentiation of LTP, demonstrating that GIRK channels are critical for depotentiation, one form of excitatory synaptic plasticity.
Learn more about receptors here:
brainly.com/question/11985070
#SPJ4
neurolemma is the named it is called
Answer:
Which type of selection tends to increase genetic variation? A. Disruptive selection B. Directional selection C. Stabilizing selection
The Answer is option A (Disruptive selection)
Explanation:
Selection can either shift the mean value of a trait, reduce the trait's variation, or increase its variation.
Genetic variation which allows natural selection to increase or decrease frequency of alleles already in the population is a source of phenotypic variation as it refers to differences in all the hereditary information of members of the same species.
Disruptive Selection is important in maintaining variation and initiating speciation as it Increases Variation by favoring alleles corresponding to more extreme phenotypes. But for it to occur, the mean phenotype has to experience the lowest fitness. Disruptive selection affects the frequency distributions of alleles and genotypes within a population.
Disruptive selection is based on the variance of a trait in a population as it increases genetic variance by equalizing the frequencies of existing alleles at polymorphic loci (a genetic loci with two or more alleles). Disruptive selection maintains and may even increase variation in natural populations by favoring extreme phenotypes, individuals with extreme values for a trait have greater reproductive success than individuals with intermediate values.
