Enslaved Natives. Because at the time they were unaware that the natives didn't have immunity towards their diseases and were very unskilled at maintaining the crops the Spanish wanted.
Desiderius Erasmus lived during a time period of significant change in 1500's Europe. This rebirth, or awakening, was being felt around the known world. During this time period in Europe, a religious renaissance was occurring. The Catholic Church, which was once the one and only church with the Pope as its all powerful leader, was beginning to be challenged by "free thinkers" who opposed some of the traditions and ideals put forth by Catholicism. This time period was also a rebirth/renaissance in the areas of technology, science, arts, and philosophy. The introduction of gunpowder, for an example, forever changed human warfare and made battles more deadly than ever.
Lots of people believe Leonardo da Vinci was the Renaissance Man because he studied many of those topics