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In molecular biology, a hybridization probe is a fragment of DNA or RNA of variable length which can be radioactively or fluorescently labeled. It can then be used in DNA or RNA samples to detect the presence of nucleotide substances that are complementary to the sequence in the probe.DNA probes are stretches of single-stranded DNA used to detect the presence of complementary nucleic acid sequences (target sequences) by hybridization. DNA probes are usually labelled, for example with radioisotopes, epitopes, biotin or fluorophores to enable their detection.
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En biología molecular, una sonda de hibridación es un fragmento de ADN o ARN de longitud variable que puede marcarse de forma radiactiva o fluorescente. Luego puede usarse en muestras de ADN o ARN para detectar la presencia de sustancias nucleotídicas que son complementarias a la secuencia en la sonda. Las sondas de ADN son tramos de ADN monocatenario utilizados para detectar la presencia de secuencias complementarias de ácido nucleico (secuencias diana) por hibridación Las sondas de ADN generalmente están marcadas, por ejemplo, con radioisótopos, epítopos, biotina o fluoróforos para permitir su detección.
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46 chromosomes and the zygote cell
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The Law of Conservation of Mass tells us that matter is neither created nor destroyed during a chemical reaction. Atoms can be rearranged to form new compounds, but the total mass of the system remains constant.
<span>Some of the more common single-gene disorders include cystic fibrosis, hemochromatosis, Tay-Sachs, and sickle cell anemia.
Even though these diseases are primarily caused by a single gene,
several different mutations can result in the same disease but with
varying degrees of severity and phenotype.</span>
