There are approximately 4.7 to 5.5 liters and 1.2 to 1.5 gallons of blood in a human's body.
Most enzymes do in fact work on a single substrate in most cases, this is because of the enzyme - substrate specificity. Certain reactant molecules acting as substrates can only fit in the "lock" of particular enzymes and undergo a conformational change and result in Unique products to be released after the reaction has occurred.
Phospholipids (lipid bilayer)
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