PDK1 (pyruvate dehydrogenase kinase 1) is an enzyme which inactivates the pyruvate dehydrogenase by phosphorylating it using an ATP molecule<span>.
</span><span>PDK1 (phosphoinositide-dependent protein kinase-1) acts by catalyzing the phosphorylation of Thr-229 (threonine at position 229 in pyruvate dehydrogenase).
This phosphorylation is </span><span>synergistic</span> with the phosphorylation of C-terminal Thr-389, but this one is not done by the PDK1.
Labeling is on..... And correct graphing lol