Scientists can use mutants to study metabolic pathways. These organisms have a mutation in a gene encoding a metabolic pathway e
nzyme that results in the inactivation of that enzyme. Saccharomyces cerevisiae (a yeast species) mutants are available that grow on fructose, but not glucose. This growth defect results from a mutation in the gene encoding what enzyme? a. phosphoglycerate kinase
b. enolase
c. pyruvate kinase
d. phostphoglycerate mutase
e. Phosphoglucose isomerase (phosphohexose isomerase or glucose-6-phosphate isomerase)
The correct answer is - e. Phosphoglucose isomerase (phosphohexose isomerase or glucose-6-phosphate isomerase)
Explanation:
Phosphoglucose isomerase (phosphohexose isomerase or glucose-6-phosphate isomerase) is an enzyme that catalyzes the conversion of the glucose-6-phosphate to fructose-6-phosphate or fructose-6-phosphate to glucose-6-phosphate.
In the given question there most likely a mutation that takes place in Phosphoglucose isomerase as it is not able to convert glucose to fructose which is a growth defect.
