Garrod hypothesized that "inborn errors of metabolism" such as alkaptonuria occur because...genes dictate the production of specific enzymes, and affected individuals have genetic defects that cause them to lack certain enzymes.
Explanation:
Archibald Garrod researched on alkaptonuria and proposed the ‘one gene-one enzyme’ hypothesis. This led to the finding that alkaptonuria is caused due to an inherited or “inborn error of metabolism”.
This hypothesis stated that each gene codes and responsible for a single specific enzyme which facilitates a particular step in the metabolic processes.
According to Garrod, a mutation of a particular gene leads to specific error or defect leading to a lack of a particular enzyme that takes part in the biochemical metabolic pathways. This disrupts the metabolic pathway at the specific enzymatic action point.
In alkaptonuria, it was found that the defective phenotype of dark urine is due to the inborn error happening during the waste elimination process.
Answer: The procedure RJ is preparing to undergo is called KIDNEY TRANSPLANT.
Explanation:
RJ was diagnosed with renal failure for the past 10 years. For him to have been in this condition for a period of 10 years depicts chronic renal failure. This is a type of kidney disease in which there is progressive loss of function of more and more nephrons that gradually decreases overall kidney function with time. The following can cause chronic renal failure:
--> Metabolic disorders: these include diabetes mellitus, obesity
--> Hypertension
--> Infections: Example is tuberculosis
--> Urinary tract obstruction
--> Congenital disorders
In chronic renal failure, the irreversible decrease in the number of functional nephrons eventually leads to KIDNEY TRANSPLANT.
Kidney transplant is a surgical procedure which is performed by a nephrologist where by a kidney from a compatible donor is transferred to a recipient. This procedure requires only one kidney from the donor, which when surgically implanted in RJ it would help perform blood filtration.
Nope i'm ok have a good day.
<span>A. Mouth, pharynx, esophagus, stomach, large intestines, small intestines</span>
