Neurons communicate with one another at junctions called synapses. At a synapse, one neuron sends a message to a target neuron—another cell.
Most synapses are chemical; these synapses communicate using chemical messengers. Other synapses are electrical; in these synapses, ions flow directly between cells.
At a chemical synapse, an action potential triggers the presynaptic neuron to release neurotransmitters. These molecules bind to receptors on the postsynaptic cell and make it more or less likely to fire an action potential.
The hemoglobin molecule has four binding sites for oxygen molecules: the iron atoms in the four heme groups. Thus, each Hb tetramer can bind four oxygen molecules.