Question

A mutation in a polypeptide with the original amino acid sequence of: Met-Ala-Gln-Arg-Glu-Leu results in a mutant with the sequence: Met-Ala-Gln-Gly-Glu-Leu. Which describes the most likely type of mutation that has occurred?

Answer 1

Answer:

This question lacks options, however, it can be answered based on general understanding of the topic

The answer is SUBSTITUTION MUTATION

Explanation:

A mutation is any change that occurs in the nucleotide sequence of a gene. Mutation can be of different types depending on how it occurs. One type of mutation is SUBSTITUTION MUTATION, which is a mutation in which one or more nucleotide base is replaced by another in the sequence.

Nucleotide bases are read in a group of three called CODON. Each of these codons specify amino acid. Hence, if the nucleotide base sequence is altered during mutation, the amino acid sequence is altered likewise. In this case where the original amino acid sequence is: Met-Ala-Gln-Arg-Glu-Leu, the mutation affected the nucleotide bases coding for Arginine (Arg), hence changing it to Glycine (Gly).

This means that a base substitution mutation occured, replacing the amino acid Arginine with Glycine in the mutated sequence.