Answer:
The correct answer is option d.
Explanation:
In a fish, the heart comprises two chambers, a ventricle, and an atrium. The deoxygenated blood comes through the body, moves into the atrium and then into the ventricle, from where it is pushed towards the body through the gills.
The pumping of the blood via the heart takes place via the capillary beds of the gills and via the tissues’ capillary beds. When the blood come in the capillary beds of the gills it gets slow down. It moves gradually via its path to the tissues and requires skeletal muscular activity to help the blood to mediate towards the heart again. Thus, a fish is dependent upon the physical effort for blood to get circulated again to the heart.
The heart of an amphibian-like the frog exhibits three chambers, two atria and one ventricle. In the process of circulation, that is, in the ventricle, the oxygenated and the deoxygenated blood gets mixed prior to being impelled out of the heart. However, amphibians possess lower metabolisms and thus, they need less oxygen. The requirement of a lesser amount of oxygen puts less pressure on the heart to provide blood with high oxygen. Thus, a heart comprising three chambers is suitable for the requirements of amphibians who could absorb oxygen via their moist skin.
Cuanto pesa y mide el hueso frontal-> How much does the frontal bone weigh and measure?
This depends on whose frontal bone you are weighing and measuring. Please include a picture for reference next time if you want specific answers.
The right answer is D.
The effectiveness of BT-Corn compared to conventional insecticide treatment is very much higher:
* The plant itself produces the toxin that blocks the digestion of or target insects: the entire plant is protected where a treatment (out of neonicotinoids, very expensive and reserved to the seed treatment) allows only a protection of surface and must be renewed several times.
* The selectivity of the treatment is very superior: each variant of the BT molecule targets only a family of insects but we do not know the impact of their cumulative effects in the environment.
Answer:
by designing a drug with steric effects on BCR-ABL1
Explanation:
Chronic myeloid leukemia (CML) is a type of cancer that affects the bone marrow and blood cells. CML is characterized by the formation of the Philadelphia chromosome, a product of a reciprocal translocation between chromosomes 9 and 22. As a consequence of this translocation, an oncoprotein tyrosine kinase called BCR-ABL1 is formed. This protein (BCR-ABL1) is responsible for 95% of all CMLs. In this case, it is possible to inhibit BCR-ABL1 (and thus inhibit CML cell proliferation) by using a kinase inhibitor. Kinase inhibitors are drugs that inhibit kinase function by preferentially binding to the inactive conformation of the target enzyme. These proteins are used to treat cancer by blocking a functional site on the kinase, thereby inhibiting its function. Moreover, it is known that steric effects alter the mode and rate by which a drug interacts with a given target. In this case, a small molecule with steric effects on BCR-ABL1, i.e., capable of altering the shape (conformation) and reactivity of BCR-ABL1, might also be used to selectively inhibit BCR-ABL1.
