The answer is osteoporosis
Osteoporosis is a condition when the bone(osteo) density is decreased, makes them look like having pore or spongy. It is found frequently in the elder woman that has been menopause for a few years.
Estrogen has a role in bone remodeling which causes a protective effect on woman before menopause.

<h2><u>My </u><u>Answer</u></h2>
In humans, cells other than human sex cells, are diploid and have 23 pairs of chromosomes. Human sex cells (egg and sperm cells) contain a single set of chromosomes and are known as haploid.
I Hope it's Helps ╮(^▽^)╭
<h2>#CarryOnLearning</h2>
The answer is; activation
The second phase of defense is called the adaptive immune response. It involved the recruitment of white blood cells (leucocytes) (mainly the B- and T- cells). The innate defense system, which is the first response to an invading pathogen, involves the body’s physical barriers such as the skin and mucous membrane.