Im not sure but B or c. Im sorry
Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
Actually a living thing is not a system. Every part of our body, like our lungs brain or heart, can be seen as a separate system. Therefore we are giant arrays of systems working together to keep you alive
You can determine it by paying attention to the unique characteristics that could only be found at heart's tissue, such as :
- looks striated or stripped
- The bundles are breached like tree but connected at both ends
hope this helps
Answer:
Haemoglobin (Hb) is a protein present in red blood cells that transports oxygen and gives blood its dark/vivid red color. The amount of haemoglobin in the blood varies from person to person. Men's levels are often greater than women's. This is scientifically proven however, it is often but not all the time.
