Turning amino acids into molecules that can be used in the Krebs cycle takes energy, which means that burning protein for fuel is not as efficient as burning carbohydrates. ... When amino acids are used as an energy source, it reduces the reserves of amino acids that are available for protein synthesis.
Such changes would occur mostly likely near or in the active binding site of the enzyme.
Because the drugs used are competitive inhibitors of the <span>HIV reverse transcriptase enzyme, it means that they connect directly to the active binding site of this enzyme not allowing it to preform its function. If the mutations impede this drugs to work, it is probably because they alter the active binding site of the enzyme, not allowing the drug to bind and have its competitive behaviour permitting the enzyme to work normally. </span><span /><span>
</span>
It is the first option. Atmospheric nitrogen is very stable so there fore hard to react with. But bacteria contain molecules that can break the bond of nitrogen.