Answer : The dissociation constant of the PFK‑inhibitor complex is, 5 µM
Explanation :
The expression for reversible competitive inhibition when apparent Km affected by addition of the inhibitor is:
![K_m_a=K_m[1+\frac{I}{K_i}]](https://tex.z-dn.net/?f=K_m_a%3DK_m%5B1%2B%5Cfrac%7BI%7D%7BK_i%7D%5D)
where,
= apparent value = 52 µM
= Michaelis–Menten constant = 40 µM
I = inhibitor concentration = 1.5 µM
= dissociation constant of the PFK‑inhibitor complex
Now put all the given values in the above formula, we get:
![52\mu M=40\mu M[1+\frac{1.5\mu M}{K_i}]](https://tex.z-dn.net/?f=52%5Cmu%20M%3D40%5Cmu%20M%5B1%2B%5Cfrac%7B1.5%5Cmu%20M%7D%7BK_i%7D%5D)
Therefore, the dissociation constant of the PFK‑inhibitor complex is, 5 µM
Explanation:
Genes are located on chromosomes, which are large pieces of DNA contained in a eukaryotic cell's nucleus.
A mechanism that is effective in maintaining a normal glomerular blood pressure only if the systemic mean arterial pressure remains between 80 and 180 mm hg is called renal autoregulation.
<h3>What is renal autoregulation?</h3>
- Autoregulation is the inner characteristic of blood vessels present in end organs, like heart, kidney, and mind, by which they dilate or constrict in response to pressure changes, thus help to keep the blood flow generally steady.
- Usually our body tries to regulate our blood pressure in range of 50 to 150 mm Hg.
- Regulation of renal blood flow and glomerular blood pressure in kidneys is called renal autoregulation.
- There are 3 mechanisms of renal blood flow namely myogenic response (MR), tubuloglomerular feedback (TGF) and third mechanism that is independent of TGF but slower than MR.
Learn more about renal autoregulation here:
brainly.com/question/28064114
#SPJ4
Evolution would least likely be a cause of natural selection.
Natural selection has to do with the survival of the fittest. Therefore, adaptation, variation, and overpopulation all have an impact on natural selection - those who do not adapt to their new surroundings due to overpopulation or those whose bodies have not modified enough will not survive.
<span>The point beneath the surface where rock breaks and an earthquake is produced is known as the focus.</span>
