Because it is easily accessible and has a mild immune response, the retina makes a good target for gene therapy.
- In a mouse model, the inner retina was highly effectively transduced by an intravitreally injected adeno-associated virus (AAV) vector.
- The vitreous and internal limiting membrane (ILM) operated as obstacles to transduction in large animals, reducing the efficacy of retinal transduction.
- Before administering AAV vectors, we performed vitrectomy (VIT) and ILM peeling on cynomolgus monkeys to get around these obstacles.
- The findings suggest that surgical ILM peeling prior to AAV vector delivery would be beneficial for retinal disease treatment and safe for effective transduction of the nonhuman primate retina.
Learn more about the adeno-associated virus (AAV) with the help of the given link:
brainly.com/question/28205495
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Answer:
. pea plants usually self-fertilize.
Answer:
Explanation:
En México se encuentran vario corredores biológicos por ejemplo el Corredor biológico Mesoamericano en los que se encuentran los estados de Chiapas, Quintana Roo, Yucatán, Campeche, Tabasco y Oaxaca.E
Rob koch is the scientist who created tests that helped confirm those things
