I think that those are the results of the cross
YYRR : YyRr : yyrr
1 : 2 : 1
25% 50% 25%
I think the top three statements are the answer.
The cell divides and grows in the organ of origin, causing a localized tumor. Cancer cells then spread to adjacent tissues or regional lymph node drainage areas, and then advance to distant organs or structures, creating metastatic tumors.