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Your question: <span>Assume that a cross is made between aabb and aabb plants and that all the offspring are either aabb or aabb. these results are consistent with ________.
Your answer: </span>Assume that a cross is made between aabb and aabb plants and that all the offspring are either aabb or aabb. these results are consistent with absolute linkage in cis.
Any queries ^?
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Answer:
a) There are lots of genes on chromosome 1 could be affected, and the gametes could be imbalanced (missing segments of DNA or whole chromosomes)
b) Roughly 50%
c) No. I would advise that the couple undergo preimplantation genetic diagnosis, so that a zygote carrying the normal copy of chromosome 1 could be selected.
Explanation:
Chromosome 1 is one of the largest and most gene rich chromosomes. An inversion that covers 70% of its length would cover lots of genes.
While an inversion on its own would not seem problematic (as all the genes on the chromosome are still there), when it comes to meiosis, the sister chromatids would not be able to correctly align, and crossing over would further complicate this. It could also lead to unbalanced gametes missing entire parts of the chromosome. Therefore, there are likely numerous genes that will be affected and messed up by the inversion.
This could explain the high incidence of past still births, as if lots of genes are affected, and non-functional, the pregnancy would be rendered non-viable, or highly deleterious causing premature death.
b) There is a 50% chance of a child inheriting the defective copy of chromosome 1 (and 50% of a chance of them inheriting the normal chromosome 1. Therefore, there is likely a 50% chance that future offspring would be affected by defects
c) No. I would advise that the couple undergo preimplantation genetic diagnosis. In this, the couple undergoes in vitro fertilization (IVF). When embryos are produced through IVF, they can then be tested for the presence of the abnormal chromosome. Embryos will only be implanted into the mother if the normal chromosome 1 is present.
This is because the traits like height, are influenced by environmental conditions around the individual. For example, there are two children born to same mother. But one is given best facilities, nutrition and care, whereas other one is brought up by a poor family, which hardly get good food to eat. His condition is much worse than the first case. In such a situation, the former child will grow up healthy and fit, and will have more height than the later one. Although, both got genes from same parent, but the environmental conditions influenced the expression of those genes differently.
Why do most cells in the human body divide infrequently? They have exited the cell cycle and entered G0. The free-energy change for the oxidation of glucose to CO2 and water is -686 kcal/mol, and the free-energy change for the reduction of NAD+ to NADH is +53 kcal/mol
