Question

Penicillin-binding protein 2a, encoded by the medA gene, isn’t affected by beta-lactam antibiotics.

Answer 1

Answer:

The correct answer is - false.

Explanation:

Penicillin-binding protein 2a or PBPs are protein produced by bacteria that binds with the β-lactam antibiotics such as penicillin. They play role in the cell wall synthesis of bacteria by producing peptidoglycan by catalyzing the reaction.

β-Lactam antibiotics bind with the PBPs and cause the disruption to peptidoglycan cross-linking in the biosynthesis of the cell wall and ultimately lysis of bacteria takes place and cell death.