Question

Hemophilia is called "the royal disease" because many European royal families had members with the condition. Hemophilia is a recessive, X‑linked disorder. Queen Victoria was unaffected by hemophilia, but was a carrier of the hemophilia gene (XHXh). Supposed Queen Victoria's husband, Prince Albert, was affected with hemophilia (XhY). What is the percent probability that a son of Queen Victoria and Prince Albert would be unaffected by hemophilia?

Answer 1

Answer:

Hemophilia was called \"the royal disease\" because many of the European royal families had members afflicted with hemophilia. Hemophilia is a sex-linked, recessive, X-chromosome disorder. It was known that Queen Victoria was unaffected but was a carrier of the hemophilia gene (XHXh).

Explanation:

Answer 2

Answer:

25%

Explanation:

In a recessive X linked disorder, a woman is said be be affected if she has both the recessive alleles on X chromosome. If she has one recessive allele then she is a carrier of the disease but she is herself normal. If she has both the dominant alleles, she is considered as absolutely normal. A carrier appears normal but she has an allele which is mutated and her progeny may be affected by the disease if her husband is not normal. It happens because females have XX chromosomes as allosomes.

In contrast to this, a male is affected by the disease even if he has one mutated/recessive allele because a male has only one X chromosome and another chromosome is Y in the allosome pair (XY chromosome). There is no other X chromosome in males which can suppress the recessive allele on the X chromosome and Y does not have any allele for this trait at all.

The given question is explained in the attachment.