I think it would be something like a landslide
Radiation
The fire radiates heat and the human body absorbs said heat.
I believe they use enzymes
The immune system and the nervous system maintain extensive communication, including 'hardwiring' of sympathetic and parasympathetic nerves to lymphoid organs. Neurotransmitters such as acetylcholine, norepinephrine, vasoactive intestinal peptide, substance P and histamine modulate immune activity.