*Sickle cell disease is a constitutional corpuscular hemolytic anemia related to an abnormal structure of the globin chain. It is an autosomal recessive disease, which means homozygosity is necessary to fully express the illness.
*It corresponds to the synthesis of an abnormal hemoglobin, HbS, which is different from normal Hb (HbA).
*The S allele (located in the chromosome 11), responsible for the anomaly, is especially widespread in the African continent, it is also found in other regions of the Mediterranean.
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*Mutation GAG to GTG leading to the substitution Glutamine by a valine in position 6 of the chain of the globine.</span>
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Answer:
Post-synaptic neurons after receiving correct ligands called as neurotransmitter in correct amount generates action potential. This action potential may be inhibitory or accelatory.
Explanation:
Postsynaptic neuron
:
These are the neurons that is present after the gap called synapse. These neurons after receiving correct ligands called as neurotransmitter in correct amount generates action potential. This action potential may be inhibitory or accelatory.
There are number of neurotransmitter. These includes
GABA ergic: This neurotransmitter is often inhibitory.
glutamatergic: This neurotransmitter is often excitatory.
Adrenergic: This neurotransmitter releases norepinephrine.
Cholinergic: This neurotransmitter activates vertebrate neuromuscular junction.
Answer:
Please find the explanation below
Explanation:
All living organisms are made up of four level of organizations namely: cell, tissue, organs, organ system and ultimately, the organism. These levels of organization are interrelated in such a way that CELLS accumulate to form TISSUE, TISSUES accumulate to form ORGAN, ORGANS accumulate to form ORGAN SYSTEM.
Since one level is dependent on a lower level, a dysfunction in one level will cause the dysfunction of another level. For example, a dysfunction in LIVER CELLS will cause the LIVER TISSUES formed from the cells to be dysfunctional. This dysfunctionality will extend to the LIVER as an organ and cause issues in the EXCRETORY SYSTEM (an organ system that constitutes the liver organ).
