I’ll like to answer but Where the question ?
During normal breathing, the brain is stimulated to breath with increasing acidity as a result of CO2 concentration from basic metabolic processes. The brain is quite selfish and only really wants to maintain it's pH which should be at a range of 7.3-7.45, and will not tolerate any decrease.
In patients who have a chronic respiratory disorder with things like COPD. The brain has become accustomed to excessive acidic content, and is now stimulated by the Hypoxic drive or by low oxygen content.
Ear muscles and tailbones are examples of vestigial structures found among the <span>Caminalcules. </span>
One strand of DNA contains many proteins.
Answer:
a. True, b. False, c.True, d. True
Explanation:
a. Base excision repair is started by a DNA glycosylase that recognizes the changes and removes the altered base by cleavage of the glycosidic bond binding the base and the deoxyribose sugar together.
b. Nucleotide excision repair works by a cut-and patch mechanism that removes their heavy lesions, including pyrimidine dimers and nucleotides . Endonucleases are responsible for the lesion of the damaged strand.
c. Nucleotide excision repair is initiated by the proteins namely UvrA, UvrC, and UvrB in Escherichia coli.
-UvrD (helicase II) later removes the damaged strand
-DNA polymerase I (PolI) fills in the resulting gap.
d. DNA glycolases removes the damaged nitrogenous base.
-It leaves the sugar-phosphate backbone intact and thus creating an apurinic/apyrimidinic site, which is commonly referred to as an AP site.
e. Xeroderma pigmentosum complementation group A(XPA)
-This is an essential protein in the nucleotide excision repair pathway.
- It helps to make a pre-incision complex along with other proteins.
