Question

Which of the following effectively describes the situation of someone with an inherited predisposition to cancer such a familial adenomatous polyposis or BRCA-associated familial breast cancer?
a) Every cell of their body contains a gain-of-function allele of an oncogene
b) Most cells in their body contain multiple cancer-causing mutations
c) If they get malignant cancer, somatic mutations will not have been a factor
d) Their cancer will most likely arise in their germ cells, not their somatic cells
e) None of the answers effectively describes the situation
f) Every cell of their body contains a defective, loss-of-function allele of a tumor suppressor gene

Answer 1

Answer:

Every cell of their body contains defective , loss of function allele of a tumor suppressor gene

Explanation:

Tumor suppressor genes - They encode Proteins that inhibit cell proliferation . But due to Loss of functional alleles in Tumor suppressor genes it leads to the development of different cancers