CD4 and CD 8 are molecules present on the surface of T cells where they interact with major histocompatibility (MHC) Molecules.
CD4 and CD8 improve T cell signalling by attaching to MHC class II (CD4) or MHC class I (CD8) molecules on APCs.
- The association of CD4 with MHC class II significantly decreases the number of antigenic peptides necessary for T cell activation (5) and significantly boosts cytokine output by helper T cells.
The MHC molecules' wide polymorphism is their distinguishing trait.
- This polymorphism is crucial for T cell antigen recognition.
- A T cell detects antigen as a peptide bound by a specific allelic variation of an MHC molecule and will not identify the identical peptide bound by other MHC molecules.
- This type of T cell activity is known as MHC limitation.
Hence, the correct answer is option C
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# SPJ4
I am pretty sure that the actual answer hides in the question itself, therefore I'd choose the second option. According to the phrase "he more successful of the two", it definitely should be B. Competition.
You dont give use the amount of info we need to answer this...
Answer:
For example, delays in mitosis are often ascribed to 'activation' of the mitotic checkpoint, a descriptor that fails to recognize that the checkpoint by definition is active as the cell starts mitosis. Conversely, the completion of mitosis in the presence of misaligned chromosomes is often automatically interpreted to indicate a defective checkpoint, even though in the absence of critical testing alternative interpretations are equally likely. In this article, we define the critical characteristics of checkpoints and illustrate how confusion generated by the inconsistent use of terminology may impede progress by fostering claims that mean very different things to different researchers. We will illustrate our points with examples from the checkpoint that controls progression through mitosis
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