Answer:
The initial step in the formation of an aminoacyl-tRNA is activation of the amino acid by reaction with ATP
Explanation:
In protein synthesis, the first step involves the formation of an aminoacyl-tRNA. This reaction is catalyzed by the the Mg²⁺-dependent enzymes known as aminoacyl t-RNA synthetases and occurs in two steps.
The first step of the reaction of the formation of an aminoacyl-tRNA is the activation of the amino acid by the attachment of an AMP molecule formed from the hydrolysis of ATP to AMP and pyrophosphate. The aminoacyl adenylate intermediate is bound to the enzyme in this initial step. Subsequently, in the second step of the activation of the amino acid, the aminoacyl adenylate intermediate is then transferred to its specific tRNA. The pyrophosphate formed in the first step is hydrolyzed to 2 phosphate molecules by a pyrophosphatase.
The overall reaction step is illustrated below:
Amino acid + tRNA + ATP -----> aminoacyl-tRNA +AMP + 2Pi
Answer:
an error in dna replication would affect many generations of cells
Explanation:
because DNA replication contains essentially all the genetic materials that will be needed in transcription and translation processes. And DNA replication is first step to ensure correct protein synthesis and others as well. But translation and transcription are both important to be exact, actually as incorrect transcription or translation could lead to useless proteins or etc.
Answer:
This disorder is caused by a recessive allele, its inheritance is sex-linked.
Explanation:
The disorder affects boys born to unaffected parents, this means that at least one of them has to be a carrier of the allele which causes the disease. So, if the allele was dominant, it would express in parents and sons. But, in this case, only is expressed in sons, so it can´t be dominant. Moreover, this condition has a sex-linked inheritance because it is always seen in boys and never in girls. This happens due to boys only have an X chromosome, so if they inherit the recessive allele of the disease, they will express it. On the other hand, girls have two X chromosomes, so if they inherit one copy of the recessive allele, they will be carriers and they won't be affected.
This disorder is never seen in females because they need to have two copies of the recessive allele. However, to have double copy, they should inherit one copy from their mothers and one copy of their fathers, but boys with the allele are affected and they die in early teens without having progeny. Therefore, a girl can't have a "carrier-father", so they will never have two copies to express the disorder.
Answer:
4.9 ^10_5
Explanation:
the negative sign after the exponent is as a result of the decimal point after the number
