If a mutation in the DNA resulted in changing a critical amino acid from valine (with -CH3 in side chain) to serine (with -OH in
side chain), it will make the new amino acid to be on the _______________ part of soluble protein inside cytoplasm.
A) Interior
B) Exterior
C) Interior and Exterior
D) Neither Interior or Exterior
E) Cannot conclude from this information
A) Interior
B) Exterior
C) Interior and Exterior
D) Neither Interior or Exterior
E) Cannot conclude from this information
1 answer:
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Answer:
Explanation:
From the question: Duchenne muscular dystrophy is an X-linked recessive disease.
Now for an X-linked recessive disorder to be affected by a male individual; it only requires the presence of only one copy of the recessive allele of the disease to be present BUT in a female individual. both copies of the recessive allele must be present.
Let the X-linked recessive disease(i.e Duchenne muscular dystrophy) be = (ⁿ)
However, we are told that the couples are normal and are unaffected. Therefore;
the male partner (XY) will be:
the female partner (XY) will be:
Similarly, the question proceeds by telling us that: the woman's brother has the disease.
Definitely, it's possible that this unaffected woman is a carrier of the disease.
So, if she is a carrier; we have her traits to be:
NOW, if a cross exist between these couples; we have
×
So, we have offspring as follows:
= normal unaffected female
= normal unaffected male
= female carrier for the Duchenne muscular dystrophy disease
= affected male with the Duchenne muscular dystrophy disease
So, the probability of the child to be affected with the disease =
Also, the probability that the first child will be a male or a female =
∴
the probability that the couple’s first child will be affected =
=