Everything explodes without it. One sentence :)
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Such changes would occur mostly likely near or in the active binding site of the enzyme.
Because the drugs used are competitive inhibitors of the <span>HIV reverse transcriptase enzyme, it means that they connect directly to the active binding site of this enzyme not allowing it to preform its function. If the mutations impede this drugs to work, it is probably because they alter the active binding site of the enzyme, not allowing the drug to bind and have its competitive behaviour permitting the enzyme to work normally. </span><span /><span>
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Answer:
During El Nino and LA Nina, opposing weather conditions are observed
Explanation:
Both El Niño and La Niña are weather patterns that occurs in the Pacific Ocean. It causes changes in global temperature and rainfall levels.