Answer:
<em>the conquest of Constantinople is an important turning point in global history because it (1) ushered in Pax Romana (2) began the Middle Ages (3) contributed to the rise of the Ottoman Empire </em><em>(</em><em>4</em><em>)</em><em> </em><em>signified the end of the Napoleonic Wars.</em>
Explanation:
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native Americans resisted the efforts of the Europeans to gain more land and control during the colonial period, but they struggled to do so against a sea of problems, including new diseases, the slave trade, and an ever-growing European population.
