Answer:
Amino acid substitutions at the interaction interface may result in binding affinity changes, and thus affect the structure of the protein complex. ... This structural change may significantly affect the binding energy, and make the protein complex unstable
Explanation:
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When alzheimer disease sets in early and impacts those under age 60, the final phase of the disease or death typically occurs around 3 to 5 years after the first signs of the disease appear. Alzheimer's disease is the most common type of dementia, which is represents the memory loss and other cognitive abilities serious enough to interfere with normal life. Alzheimer accounts for about 60 to 80 percent of dementia cases.
Answer:
When jobs are outsourced to different countries,the resultant effect is that the morale in the workplace would drop drastically which would end up bringing bad publicity to the company. Outsourcing has been known to cause high unemployment rate, loss of income and loss of competitive advantage thereby leaving people without financial support and employment.
