Answer:
Leptin is a protein hormone composed of 167 amino acids of the cytosine family, it is synthesized mainly by white adipose tissue. The leptin receptor is related to that of receptors for cytosines (since it uses Janus or JAK type kinases and STAT-3 proteins as intracellular mediators of transcription pathway), it is predominantly found in the hypothalamus (particularly in the arcuate nucleus and to a lesser extent in the nuclei dorsomedial and ventromedial), hippocampus and cerebellum. There is evidence that leptin acts at the level of the arcuate nucleus, preventing the formation of NPY.
Explanation:
Leptin is produced exclusively in adipose tissue cells in a wide variety of species, including humans, and its concentration is higher in overweight than in lean individuals. The biological actions of leptin can be classified into two groups, those that are exerted in the tissues of the central nervous system, mainly the hypothalamus, and those that are carried out on the peripheral tissues. The former regulate body weight downward, decrease food intake, increase basal energy expenditure and modify some neuroendocrine functions such as reproduction, while the latter have effects on proliferation, differentiation and metabolism of peripheral tissues. The leptin that reaches the hypothalamus, in addition, inhibits protein synthesis and the secretion of neurons producing NPY / AgRP of the arcuate nucleus and stimulates the synthesis and secretion of those containing POMC. NPY (neuropeptide Y) is produced in the hypothalamic arcuate nucleus. This neurotransmitter arrives through the projections of the neurons of said nucleus to the paraventricular nucleus, which is the area where it is released. There are several studies that have shown that an increase in NPY leads to an increase in the sensation of hunger and thus to hyperphagia and obesity. Leptin acts at the level of the arcuate nucleus, preventing the formation of NPY. The leptin receptor lacks enzymatic activity in its intracellular domain. Instead, it is linked to members of the janus kinase family, which belong to a class of tyrosine kinases. The binding of the ligand activates the Jak kinase and leads to the phosphorylation of certain cytoplasmic proteins. Within these proteins there is a class of cytoplasmic transcription factors called signal transducers and activators of transcription (STAT).
Answer:
Red because that's the color we see.
Plants need to have chloroplasts, because chloroplasts are responsible for converting solar energy into chemical energy. By doing this, the plant is able to perform photosynthesis, which then provides the food energy that the plant needs. Without chloroplasts, the plant would die.
Answer:
Nitrogenous bases contain the genetic information, their amount is variable among different species, and the arrangement of these bases is also variable among different species
Explanation:
Both Watson-Crick and Pauling's DNA models considered that DNA nitrogenous bases (i.e., Adenine, Cytosine, Thymine and Guanine) contain the genetic information that determines the characteristics of living organisms. Moreover, both DNA models also considered that nitrogenous base composition varies between species, as well as the arrangement of these bases in the DNA chain also varies between species. Based on these features, Linus Pauling considered that a model where nitrogenous bases would be arranged on the outside of the DNA molecule would be easier for the DNA molecule to be replicated, transcribed, or repaired. Although incorrect, Pauling's DNA triple helix model was fundamental to develop the helical (double-stranded) structure of DNA, which was finally discovered by Watson and Crick in 1953.
Answer:B
Explanation:
Just did this in usatestprep
