The dicer enzyme processes dsRNA and forms siRNAs, which suppress the expression of target genes by cutting mRNA. 1) siRNA 2) RNA.
<h3>What are siRNA fragments?</h3>
siRNA means small interfering RNA. This is a silencing RNA molecule involved in the RNA interference mechanism, intervening in the expression of a specific gene.
siRNAs are complementary double-stranded RNA molecules composed of about 20-21 nucleotides. siRNA originates from a long double-stranded RNA (dsRNA).
The dicer enzyme cuts dsRNA molecules and produces siRNA. siRNAs suppress the expression of target genes when cutting messenger RNA.
siRNAs suppress the expression of target genes by cutting the complementary messenger RNA (mRNA) into two halves. This is accomplished by the interaction of the siRNA with the RISC complex (RNA-induced silencing complex).
The two mRNA halves are later degraded by the cellular machinery, leading to the suppression of the gene expression.
siRNAs also participate in other pathways related to RNAi, such as in antiviral defense or in the chromatin structure organization.
RNA interference is a mechanism of eukaryotic gene regulation. In this mechanism, the enzyme dicer cuts dsRNA into smaller fragments called (1) siRNA, which form a complex with RISC and degrade specific (2) RNA.
You can learn more about siRNA at
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