Question

Psedoephedrine (Sudafed) is a beta agonist drug that is used to relieve symptoms of nasal congestion in persons with allergic rhinitis or a common cold. Based on your understanding of beta agonist drugs, please explain why the box has warning against use of this drug in perosns with heart disease, hyperetension, glaucoma, and urinary retention.

Answer 1

Answer:

For heart disease and hypertension: Because they contain NSAIDs. It can raise blood pressure and cause other related problems.

For glaucoma: Because is a selective alpha-1 adrenergic receptor agonist, which can induce angle closure by mydriasis. People with glaucoma have narrow drainage angles.

For urinary retention: It can cause urinary retention because of its systemic action on α-adrenergic receptors.