Answer:
Since sickle cell disease is a disorder with an autosomal dominant inheritance pattern, and in light of the lack of data, it could be said that the only way for Pat and Tracy to have a child with sickle cell disease is for both of them to be healthy carriers of the gene, with a 25% probability.
Explanation:
Considering that both Pat and Tracy each have a sibling with a sickle cell trait and that both they and their parents are healthy, it must be assumed that some of their parents are healthy carriers:
- Pat and Tracy do not have sickle cell trait. In this case, there is no chance that they will have a child with sickle cell disease.
- Either Pat or Tracy has the trait, but the other does not. It is possible that at least one of their children is a healthy carrier.
- If both Tracy and Pat have sickle cell trait, the chances of having a child with sickle cell disease are:
Alelles R r
R RR Rr
r Rr rr
RR: healthy (25%).
Rr: healthy carrier (50%).
rr: sickle cell disease (25%).
<em>If Pat and Tracy are healthy carriers of the gene that determines sickle cell disease, the chance of having a child with the disease is 25%</em>.
Learn more:
Autosomal recesive inheritance brainly.com/question/10605612
The order is calcification of matrix >> cells differentiate into osteoblasts >> formation of the primary ossification >> osteoclasts break down the spongy bone >> formation of the secondary ossification (5,3,1,2,4). It is a fundamental process.
<h3>What are osteoblasts?</h3>
Osteoblasts are cells of the bones, which act to generate bone matrix and modulate the process of mineralization of the skeleton.
Endochondral ossification refers to the mechanism through which the cartilaginous bones generate longitudinal growth.
This mechanism (endochondral ossification) is fundamental during fetal/embryo development.
Learn more about endochondral ossification here:
brainly.com/question/5325975
<span>The 5' end
During transcription, new nucleotides are added to the 3' end of the molecule due to the arrangement of the nucleotide with the new nucleotide being added to the hydroxyl group at the 3' position of the ribose.</span>
